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Central actions of somatostatin in the generation and control of breathing Biol. Res.
Llona,Isabel; Eugenín,Jaime.
The neuropeptide somatostatin is involved in many functions in the central nervous system as well as in the periphery. When it is centrally injected, an irreversible apnea is often developed. In the present review, we discuss the effects of somatostatin as the result of its actions at three levels of the respiratory neural network: a) by modulating the output of cranial or spinal motoneurons; b) by altering the genesis of the respiratory rhythm in the brainstem; and c) by regulating the chemosensory drive input into the respiratory pattern generator
Tipo: Journal article Palavras-chave: Apnea; Brainstem; Chemoreceptors; Respiratory rhythm.
Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400006
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Gender and age differences in polysomnography findings and sleep complaints of patients referred to a sleep laboratory BJMBR
Silva,A.; Andersen,M.L.; De Mello,M.T.; Bittencourt,L.R.A.; Peruzzo,D.; Tufik,S..
Our objective was to examine the effet of gender on the sleep pattern of patients referred to a sleep laboratory. The data (questionnaires and polysomnographic recordings) were collected from a total of 2365 patients (1550 men and 815 women). The polysomnography permits an objective assessment of the sleep pattern. We included only polysomnography exams obtained with no more than one recording system in order to permit normalization of the data. Men had a significantly higher body mass index than women (28.5 ± 4.8 vs 27.7 ± 6.35 kg/m²) and had a significantly higher score on the Epworth Sleepiness Scale (10.8 ± 5.3 vs 9.5 ± 6.0), suggesting daytime sleepiness. Women had a significantly higher sleep latency than men, as well as a higher rapid eye movement...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sleep; Gender; Polysomnography; Apnea; Insomnia; Database.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200005
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The reciprocal interaction between sleep and type 2 diabetes mellitus: facts and perspectives BJMBR
Martins,R.C.; Andersen,M.L.; Tufik,S..
Type 2 diabetes mellitus is a systemic disease characterized by intolerance to glucose and peripheral resistance to insulin. This endocrine disease affects fundamental mechanisms of the central nervous system and jeopardizes the balance of vital functions such as the cardiovascular and circadian rhythm. The increased prevalence of metabolic disorders in our society is aggravated by endemic voluntary postponement of bedtime and by the current sedentary lifestyle, leading to epidemic proportions of obese people. Diabetes and chronic loss of sleep share the fact that both affect millions and one is detrimental to the other. Indeed, sleep deficits have marked modulatory effects on glucose metabolism and insulin sensitivity and foster metabolic syndrome that...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diabetes; Metabolic syndrome; Obesity; Apnea; Sleep.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000300001
Registros recuperados: 3
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